New Study Links Common Chemical PCE to Severe Liver Damage

Published By DPRJ Universal | Published on Saturday, 27 December 2025

A new study in Liver International links tetrachloroethylene (PCE), a chemical in dry-cleaning and household products, to severe liver damage. Researchers found individuals with detectable PCE levels were three times more likely to have significant liver fibrosis. PCE can also contaminate air and water, posing risks, especially to children due to their higher metabolic rates and behaviors. Experts advise avoiding PCE-containing products, using water-based alternatives, ensuring good ventilation, and airing out dry-cleaned clothes to reduce exposure and protect family health.

New research published in Liver International reveals a strong link between exposure to tetrachloroethylene (PCE) and severe liver damage, including fibrosis that can lead to liver cancer or failure. PCE, a chemical commonly used in dry-cleaning and household items like spot removers and stainless steel polishes, was detected in 7% of study participants, who were three times more likely to have significant liver fibrosis. Medical toxicologists emphasize that PCE's harmful effects may be broader than previously confirmed, noting it's also a likely human carcinogen and can cause neurological effects like dizziness and headaches.PCE is a volatile chemical that can persist in indoor air, enter groundwater, and build up in porous materials, making it a widespread public health concern. Children are particularly vulnerable due to their higher metabolic rates, increased air intake relative to body size, and hand-to-mouth behaviors. PCE can be found in various household products, including carpet cleaners, glues, and even dry-cleaned clothing.To protect families, experts recommend several practical steps: always read product labels and avoid those listing tetrachloroethylene or perchloroethylene, opting for water-based or 'green' alternatives. Improve ventilation by opening windows and using exhaust fans when using cleaners. When using dry-cleaning services, choose those employing 'wet cleaning' or liquid carbon dioxide methods. Always remove plastic wrap from dry-cleaned items and air them out in a well-ventilated space before bringing them inside, especially keeping them out of nurseries.