Scientists Warn of Widespread Toxic Chemical TFA in Eastern NC

Published By DPRJ Universal | Published on Friday, 26 December 2025

Scientists have discovered high levels of TFA, a potentially harmful PFAS compound, in blood and water samples across Eastern North Carolina, with Chemours' Fayetteville plant identified as a significant source. Despite industry claims of low toxicity, studies suggest TFA, a 'regrettable substitute' for ozone-depleting chemicals, is widespread globally and poses risks, including reproductive harm. Concerns are mounting over Chemours' planned expansion and the weakening of environmental regulations, prompting local communities to oppose further contamination.

A recent study led by environmental epidemiologist Jane Hoppin from N.C. State University revealed alarming levels of Trifluoroacetic acid (TFA), a short-chain PFAS chemical, in archived blood samples from Wilmington residents and local water supplies. This discovery challenges industry assertions that TFA is benign, with evidence suggesting potential reproductive toxicity. The research identified Chemours' Fayetteville Works plant, located 80 miles upstream, as a major contributor to the widespread contamination of the Cape Fear River, with TFA concentrations far exceeding health guidance levels in downstream areas. TFA is a 'regrettable substitute' developed after the phase-out of ozone-depleting CFCs, now found in diverse products like refrigerants and pesticides. Global TFA levels have surged dramatically, raising concerns about irreversible environmental and health impacts. Despite these findings, the Environmental Protection Agency has weakened some PFAS regulations, and Chemours plans to expand its Fayetteville facility, prompting strong opposition from local governments and environmental groups. Critics highlight Chemours' history of lacking transparency regarding emissions and contamination. Efforts by the Southern Environmental Law Center are underway to compel state regulators to impose limits on TFA discharges and ensure public access to critical information, as communities grapple with decades of PFAS pollution and the ongoing struggle for accountability and cleaner water.